The scientific research center in Jamraya was established during the 1980s and is believed to be one of the most important research centers in the country.
"Our air defenses are confronting an Israeli missile attack on one of our sites in the Damascus suburbs and three of the targets were downed", state news agency SANA reported.
With details still emerging on Israel's Friday attack against a military site south of the Syrian capital city of Damascus, a strike which Israeli media have presented as being an attack against Iran, a new round of strikes was reported Monday night, against different targets in metro Damascus.
There was no official Israeli comment.
Reports also said that Syrian forces intercepted three of the six missiles fired by Israel.
If true, this would be the first reported operational use of the Jericho 1 ballistic missile.
While Syria and Israel, which have never signed a peace treaty, have repeatedly exchanged multiple tit-for-tat attacks, Netanyahu along with the country's defense minister stated that Tel Aviv is free to act in Syria for the sake of its security.
A satellite image showing the results of an alleged Israeli airstrike on a reported Iranian base being set up outside Damascus, from November 16, 2017. "We wanted to make sure he and the leadership in Iran understood that in a way that was crystal clear".
Images of the base broadcast by the BBC showed "a series of two dozen large low-rise buildings, likely for housing soldiers and vehicles".
Israel has long viewed Iran as its enemy number one.
Israel in the past has targeted positions of Lebanon's powerful Hezbollah group inside Syria where the Iran-backed group is heavily involved in fighting alongside the Syrian army.
He said that Iran maintained a "legitimate" presence in Syria, according to the Interfax news agency.
The statement came as officials from the US National Security Council flew into Israel for talks with security heads, primarily over the US-Russia agreement. They were expected to discuss Iran's alleged construction of the military base at al-Kiswah.
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